3 edition of Human tumor viruses found in the catalog.
Human tumor viruses
Includes bibliographical references and index
|Statement||edited by Dennis J. McCance|
|Contributions||McCance, Dennis J|
|LC Classifications||QR372.O6 H87 1998|
|The Physical Object|
|Pagination||x, 363 p. :|
|Number of Pages||363|
|LC Control Number||98012185|
Human T-cell leukemia virus type, also called human T-lymphotrophic virus (HTLV-1) is linked to adult T-cell leukemia/lymphoma. It is spread through infected semen, vaginal fluids, blood and breast milk. The infection is rarely found in the United States. The effects of these viruses on cancer development is highly complicated. Purchase Human and Related Viruses - 1st Edition. Print Book & E-Book. ISBN ,
Human papillomaviruses (HPVs) are small DNA tumor viruses that can transform squamous epithelia. HPVs replicate their own genomes by reprogramming the host cell’s DNA replication machinery. The high-risk HPV E6 and E7 oncoproteins target negative growth regulatory signaling in the host cell to enable viral genome replication in these. An oncovirus is a virus that can cause term originated from studies of acutely transforming retroviruses in the –60s, when the term "oncornaviruses" was used to denote their RNA virus origin. With the letters "RNA" removed, it now refers to any virus with a DNA or RNA genome causing cancer and is synonymous with "tumor virus" or "cancer virus".
The book also describes the structure and chemistry of many known viruses such as the papovaviridae, herpes virus, poxvirus, coronavirus, or the Bunyamwera supergroup. The book then explains the structure and function of the animal cell including the cytoplasmic organelles, the nucleus, inhibitors of cell function, and viral multiplication. Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology provides an up-to-date introduction to human, animal and plant viruses within the context of recent advances in high-throughput sequencing that have demonstrated that viruses are vastly greater and more diverse than previously recognized. It covers discoveries such.
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In the 34 years since the isolation of Epstein-Barr virus there has been an accumulation of evidence linking some important human cancers and viruses. This book describes the molecular biology and pathogenesis of these viruses, including Human tumor viruses book only recently associated with human cancers.
It provides an up-to-date account of the progress in our knowledge of the virus/host interactions which. SV40 and Polyomavirus. The best studied DNA tumor viruses, from the standpoint of molecular biology, are probably simian virus 40 (SV40) and gh neither of these viruses is associated with human cancer, they have been critically important as models for understanding the molecular basis of cell utility of these viruses in cancer research has stemmed from the.
DNA TUMOR VIRUSES INVOLVED IN HUMAN CANCERS. The first DNA tumor viruses to be discovered were rabbit fibroma virus and Shope papilloma virus, both discovered by Richard Shope in the s. Papillomas are benign growths, such as warts, of epithelial cells. They were discovered by making a filtered extract of a tumor from a wild rabbit and.
In addition, the book covers the individual aspects of seven oncogenic viruses, i.e., hepatitis B virus, hepatitis C virus, human papilloma virus, Epstein-Barr virus, human T-cell lymphotropic virus, Kaposi sarcoma-associated herpes virus, and Merkel cell polyomavirus, and the related human cancers.
However, when viruses are isolated from tumor tissue, they may contain acutely transforming viruses (e.g., Rous sarcoma virus [RSV]) that are capable of rapidly reproducing the same type of tumor.
Rous sarcoma virus was found to contain an additional gene, src, which is responsible for the transforming activity of the virus. Viruses and Human Cancer provides a comprehensive review of the seven currently known human tumor viruses and their associated cancers with an emphasis on epidemiology, clinicopathologic features, and pathogenesis.
Chapters are written by internationally recognized experts, and all are generously illustrated with tables, diagrams, and photographic images.
On the other hand, SV40 is a tumor virus, causing tumors in rodent. We will learn how T-antigen, a viral oncoprotein, contributes to the viral oncogenesis. Importantly, T-antigen dysregulates tumor suppressor gene products—p53 and Rb.
Recently, several human polyomaviruses including JCV, BKV, and Merkel cell polyomavirus (MCV) have been. This article is the second of a 2-part series on cancer virology. An introduction to the infectious causes of cancer can be found here.
Human tumor viruses account for an estimated 12% to 20% of cancers worldwide. Viruses can lead to cancer by associating with host proteins, proliferating when the human immune system is weakened, and hijacking proliferating human cells.
RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On the Frontiers of Understanding Proceedings of the International Conference on RNA Tumor Viruses in Human Cancer, Denver, Colorado, June 10–14, Editors Search within book.
Front Matter. Pages i-xxi. PDF. HBV causes viral hepatitis. Hepatitis is an inflammation of the liver. Many people with HBV go on to recover following an acute infection. However, some develop a chronic (long-term) HBV infection. Epstein-Barr virus, human papilloma virus, hepatitis B virus, and human herpes virus-8 are the four DNA viruses that are capable of causing the development of human cancers.
The presence of viral gene products in tumor cells that require them to maintain their unchecked proliferation, can provide important targets for directed therapies that. Both DNA and RNA viruses have been shown to be capable of causing cancer in humans.
Human T lymphotrophic virus type 1 and hepatitis C viruses are the two RNA viruses that contribute to human cancers. Hepatitis C virus is an enveloped RNA virus capable of causing acute and chronic hepatitis in humans by infecting liver cells. DNA Tumor Viruses In Human Cancer Squamous cell carcinoma: Larynx Esophagus All histologically similar Lung 10% of human cancers may be HPV-linked Papilloma Viruses urogenital cancer wart malignant squamous cell carcinoma Papilloma viruses are found in 91% of women with cervical cancer.
The book concludes by evaluating the possibility of direct etiologic involvement of either endogenous or exogenous RNA tumor viruses in human cancers. This book will be of value both to graduate students and to established investigators with specific interest in Book Edition: 1.
Viruses and Human Cancer provides a comprehensive review of the seven currently known human tumor viruses and their associated cancers with an emphasis on epidemiology, clinicopathologic features, and pathogenesis. Chapters are written by internationally recognized experts and all are generously illustrated with tables, diagrams and photographic images.
Re search in recent years has shown that human tumors have a multifactorial nature and that some DNA tumor viruses may playa key role in their etiology. The aim of this book is to assess our knowledge of DNA tumor viruses by reviewing animal models, mechanisms of transformation, association with human tumors, and possi bilities of.
Buy RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On the Frontiers of Understanding by Philip Furmanski, Jean Carol Hager from Waterstones today. Click and Collect from your local Waterstones or get FREE UK delivery on orders over £ Abstract. Table 1 lists possible interactions of viruses in oncogenesis and emphasizes the role of human pathogenic viruses.
The majority of tumor viruses known today insert their genetic material into the host cell nucleus, where it persists. Get this from a library. Human tumor viruses. [Dennis J McCance;] -- "In the 34 years since the isolation of Epstein-Barr virus (EBV) there has been an accumulation of evidence linking some viruses with important human cancers.
This new book describes the molecular. Explore the latest full-text research PDFs, articles, conference papers, preprints and more on IMMUNOSENESCENCE. Find methods information, sources, references or conduct a literature review on.
Summary. Viruses are responsible for about 15% of the world’s cancers. Up to 80% of these human viral-associated cancers are cervical cancer (associated with human papilloma virus or HPV) and liver cancer (associated with the hepatitis B virus or HBV and the hepatitis C virus or HCV).Epstein-Barr virus (EBV), human herpesvirus 8 (HHV8), and human T-lymphotropic virus 1 (HTLV-1) showing lymphocytes tropism (Akram et al., ) are human viruses directly associated with cancer.
Anecdotal observations of spontaneous cancer regressions coincidental with viral infections have indicated that viruses may preferentially infect cancer cells, and several promising oncolytic viral therapies are being developed to fight human tumors.
9,10 Whether viral infections and lysis of cancer cells is a common natural phenomenon remains.